Novel coronavirus vaccine side effects! Be sure to watch it before you get vaccinated

At present, what are the side effects of the six novel coronavirus vaccines, namely, Modena, Pfizer, Johnson & Johnson, AstraZeneca, Russian satellite 5 and China Kexing? In order to control the epidemic situation, the world has stepped up the application of the novel coronavirus vaccine, but the side effects of the vaccine have also deterred many people

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At present, what are the side effects of the six vaccines, namely, Modena, Pfizer, Johnson & Johnson, AstraZeneca, Russian satellite 5 and China Kexing? Are these normal side effects? The side effects of the novel coronavirus vaccine are mainly divided into two categories: the common side effects of the novel coronavirus vaccine are mainly divided into two categories: ● local side effects of the injection site, such as pain, redness and swelling

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● systemic side effects such as fatigue, headache, myalgia, arthralgia, fever and chills

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Most of these symptoms appear within three days after vaccination, and will disappear in two or three days

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Let’s break a myth

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Many people think that the side effects of vaccines are terrible

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In fact, it is normal that vaccines cause general side effects

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This is because, when the vaccine is injected into the human body, it needs to stimulate the immune system to produce an immune response and stimulate antibodies

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In this way, the vaccine can play a role in resisting the virus

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The injection site pain, swelling, fatigue, fever, headache, etc

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are the reactions that accompany the body’s immune response, that is, the signs that the immune system is activated and begins to work

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It also shows that the immune system is learning how to fight the new coronavirus and build up a certain immunity

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Some people do not respond to the vaccine

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In this case, there is no need to worry about whether the antibody is generated or not

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In the end, it is not based on the physical reaction, but on the antibody detection

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From the phase III clinical data, most people will have some adverse reactions (just like a severe cold) after receiving the vaccine

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It should be said that the body’s reaction to the novel coronavirus vaccine is relatively large

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However, we are talking about general side effects

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If unexpected and serious adverse reactions occur, we must pay special attention to them

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Which of the six new coronal vaccines has the least side effects? According to the clinical trial data of each novel coronavirus vaccine, we can know the general side effects

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Many people ask, which vaccine has high side effects and which one has less side effects? In fact, strictly speaking, the data of different vaccines can not be directly compared, because they are not carried out under the same clinical trial conditions – different regions, different hospitals, different medical staff, different subjects, so there will be systematic errors

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But we can see some trends from the comparison of these data

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List of side effects of six vaccines: list of side effects of six vaccines of Modena, Pfizer, Johnson & Johnson, AstraZeneca, Russian satellite 5 and China Kexing

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(health 1 + 1) 1

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Common side effects of Modena vaccine, second dose data

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Modena vaccine belongs to mRNA vaccine

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According to the clinical data of Modena phase III, the most common adverse reaction was pain at the injection site, which occurred in 80% of the patients

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The other adverse reactions, such as erythema and swelling, were less than 10%

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After injection of Modena, some people also have symptoms of lymphadenopathy, which is also caused by the immune system stimulated by the vaccine

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They usually recover naturally within a week

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However, if the swelling and pain continue for more than a week, and the discomfort does not ease with time, but aggravates, it is recommended to further consult a doctor

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The main side effects of Modena were fatigue, headache and muscle pain

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The side effects of the second injection were more than those of the first injection

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2

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Pfizer vaccine common side effects of Pfizer vaccine, second dose data

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Pfizer vaccine is also a mRNA vaccine, and the common local side effects are similar to those of Modena, including pain, erythema and swelling; the most common systemic side effects are fatigue, headache and muscle pain, and the incidence is slightly lower than that of Modena

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[2] [3] after the second injection of Pfizer vaccine, the local side effects did not change significantly, but the systemic side effects increased significantly

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3

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Common side effects of AstraZeneca vaccine, first dose and standard dose data

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AstraZeneca vaccine is an adenovirus vector vaccine

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Its main local side effects are pain, tenderness and skin fever

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Systemic side effects are similar to those of other vaccines

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In clinical studies, AstraZeneca was tested at high (standard) and low doses, as well as in people of different ages

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The results showed that the higher the injection dose, the younger the people, the more side effects

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This is because the young people have strong immunity, and the body reaction is also greater after the vaccination

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Unlike other vaccines, the side effects of the second dose are less than those of the first

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Recently, AstraZeneca vaccine has attracted much attention due to thrombosis

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Currently, the European Drug Administration (EMA) has concluded that thrombosis is not directly related to vaccine

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In fact, many people may not have noticed that during the phase III clinical trial of AstraZeneca, two cases of spinal cord inflammation were reported, which is the same unexpected adverse event as thrombosis

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At that time, the clinical trial was suspended, and the independent expert committee confirmed that one case was not related to the vaccine, but the other case might still be related

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Later, the experiment recovered and the neurological events were continuously monitored

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4

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Common side effects of Johnson & Johnson vaccine

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Johnson & Johnson vaccine is the only vaccine that only needs one shot at present

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It is also an adenovirus vector vaccine, and its local side effects are very similar to other vaccines

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The main adverse reaction is pain, and other side effects such as erythema and swelling are rare

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The systemic side effects caused by Johnson & Johnson vaccine are also fatigue, headache and muscle pain

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The incidence of adverse reactions in young people (18-55 years old) was significantly higher than that in the elderly (over 65 years old)

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5

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Russian satellite V vaccine Russian satellite V vaccine is a mixed adenovirus vector vaccine

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The main side effects are flu like symptoms

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6

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Common side effects of China Kexing vaccine

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China’s Kexing vaccine has been widely vaccinated in Chinese mainland and Hongkong, and is very concerned by Chinese

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At present, there are only phase I and phase II clinical research data of Kexing vaccine

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The number of vaccinated people participating in the trial is only 348, and the adverse reaction rate is significantly lower than that of other vaccines, which is only more than 20%

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From an academic point of view: 200 words are omitted here

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We have been looking forward to the large-scale clinical data of phase III of Kexing

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Unfortunately, we still haven’t seen it published

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In addition, the number of patients enrolled in the phase I-II clinical study is small, so the adverse events of Kexing vaccine are still difficult to judge..

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