[6 children’s paradise · broadcast] these questions about the new coronavirus vaccination are answered once and for all!

Buddies have been budding since the novel coronavirus vaccination program was launched

.

All the partners are closely monitoring the vaccination trend

.

The COVID-19 vaccination daily receives many messages from the buddy and the official account in the video and public numbers

.

In order to let you know more about the new coronavirus vaccination, Xiao Bian will answer these questions one by one today

.

Follow Xiao Bian to have a look! Vaccine type 01 inactivated vaccine vaccinated with new coronavirus vaccine as soon as possible

.

The new coronavirus inactivated vaccine products approved for marketing conditionally are respectively produced by Sinopharm Group China biology Beijing Institute of Biological Products Co., Ltd

.

(Beijing Institute), Wuhan Institute of Biological Products Co., Ltd

.

(Wuhan Institute) and Beijing Kexing Zhongwei Biotechnology Co., Ltd

.

(Kexing Zhongwei)

.

The principle is to use Vero cells to culture and amplify the virus β The virus was inactivated by propionolactone, the antigen was retained to induce immune response, and aluminum hydroxide adjuvant was added to improve the immunogenicity

.

In order to further guarantee the supply of novel coronavirus vaccine, Sinopharm China biological Co., Ltd

.

has made overall arrangement of domestic resources to expand the production capacity of novel coronavirus vaccine stock solution and the preparation packaging capacity

.

At present, Sinopharm Sinopharm is making use of the packaging capacity of its affiliated institutes of biological products such as Changchun, Lanzhou, Chengdu and Haihai to expand the production capacity of novel coronavirus vaccine

.

According to the provisions of the marketing license holder system, Beijing Institute of biological products has entrusted Lanzhou Institute of biological products, Chengdu Institute of biological products, Changchun Institute of biological products and other enterprises to undertake the sub packaging task of Beijing Institute of biological products Xinguan vaccine preparation, which is also in line with international practice

.

02 adenovirus vector vaccine new coronavirus vaccine should be inoculated as soon as possible

.

The adenovirus vector vaccine approved for marketing conditionally is the recombinant new coronavirus vaccine (type 5 adenovirus vector) produced by kangxinuo biological Co., Ltd

.

(kangxinuo)

.

The principle is to recombine the spike glycoprotein (s protein) gene of the new coronavirus into the replication deficient human adenovirus type 5 gene, and the recombinant adenovirus expresses the S protein antigen of the new coronavirus in vivo to induce immune response

.

03 recombinant subunit vaccine vaccinated with new coronavirus vaccine as soon as possible

.

The recombinant subunit vaccine approved for emergency use is the recombinant new coronavirus vaccine (CHO cell) produced by Anhui zhifeilongkema biopharmaceutical Co., Ltd

.

(zhifeilongkema)

.

The principle is to recombine the S protein receptor binding region (RBD) gene of new coronavirus into the gene of Chinese hamster ovary (CHO) cells, express it in vitro to form RBD dimer, and add aluminum hydroxide adjuvant to improve the immunogenicity

.

At present, there are five kinds of vaccines in China

.

According to the published phase III clinical data, the effective rate of the two vaccines of Sinopharm group is 79%, the effective rate of Zhongsheng Wuhan and Zhongsheng Beijing Kexing biological vaccine is 50% – 83%, and the overall effective rate of adenovirus vector vaccine developed by academician Chen Wei team of Academy of Military Sciences and kangxinuo biological is 65.7%

.

Anhui Zhifei recombinant protein vaccine, phase III clinical data has not yet come out

.

The results of phase I and phase II clinical trials showed that the neutralizing antibody titer of Zhifei vaccine was higher than that of inactivated vaccine

.

However, Anhui Zhifei needs three injections and three runs

.

If it’s too much trouble, choose other vaccines

.

Why is there an urgent need to vaccinate Xinguan vaccine? It’s very safe in China

.

Don’t you need to vaccinate? If other countries have been vaccinated and China opens its door again in the future, the vast majority of people in China will be in a non immune state, which is likely to cause another outbreak—— Zhong Nanshan, academician of the Chinese Academy of Engineering (CAE)

.

According to the latest statistics on the 28th, there are 17997267 confirmed cases and 201187 deaths in India

.

India has confirmed more than 300000 cases for the eighth consecutive day! Compared with the published data, the actual number of cases will be higher, because many infected people have not been detected

.

Moreover, the progress of vaccination in India is very slow

.

At present, India has less than 10 doses of novel coronavirus vaccine per 100 people

.

Such a low vaccination rate can not effectively stop the spread of the virus

.

Insufficient testing and vaccination actually reflect the backwardness of public health work in India

.

In addition, India’s national education level is relatively backward, many people still do not believe in the threat of the new coronavirus

.

Since the March 11 pilgrimage to kumbhmela in India, millions of Hindus have gone to bathe in the Ganges River, leading to a sharp increase in new cases in India

.

India out of control, let the world pay the price? The outbreak of COVID-19 in India is not a matter of a country, it is a result of challenging the world’s epidemic, or even a harsh warning

.

There are two main impacts: first, if the epidemic situation in India is not well controlled, it will not only become a super exporter of the virus, but also lead to the emergence of more mutated viruses, affecting neighboring and even further countries

.

Second, and more importantly, the outbreak in India may lead to a global shortage of vaccines

.

As mentioned above, India is the largest vaccine producer in the world

.

Many European and American pharmaceutical companies set up factories in India or entrust Indian enterprises to manufacture vaccines

.

Who for the free supply of novel coronavirus vaccines to less developed areas   In the covax program, more than 80% of the vaccines are currently produced in India

.

What should China do? The tragedy of India enlightens us as follows: first, to speed up vaccination, China’s current vaccination rate is far from reaching the barrier of mass immunization

.

No matter how complete a person’s protection is, it can’t match the group’s defense

.

Those who still feel that “there is no epidemic in China, no need to get vaccinated” should not hesitate

.

Second, strict social and individual prevention and control measures should be carried out

.

We should do a good job in “external prevention and control, internal prevention and control”

.

Once the prevention and control is relaxed, the epidemic situation may revive at any time

.

The specific population of 0160 years old and above and the population of 60 years old and above are the high risk population of severe and death after infection with new coronavirus

.

At present, the number of phase III clinical trials of four new coronavirus vaccines approved for marketing is limited, and there is no data on the protective effect of the vaccine on this population

.

However, the data of phase I / II clinical study showed that the safety of vaccination in this population was good

.

Compared with the population aged 18-59, the titer of neutralizing antibody after vaccination was slightly lower, but the positive conversion rate of neutralizing antibody was similar, suggesting that the vaccine would also have a certain protective effect on the population aged over 60, so vaccination is recommended

.

02the clinical trial data of the existing vaccines for people under the age of 18 have not been obtained, so it is not recommended to vaccinate people under the age of 18

.

03 chronic patients group chronic patients group is a severe and high risk group of death after infection with new coronavirus

.

The chronic patients with stable health and good drug control are not taboo population for new coronavirus vaccination, so vaccination is recommended

.

04 if women of childbearing age and lactation get vaccinated after vaccination or in the case of unknown pregnancy, based on the understanding of the safety of the above vaccines, it is not recommended to take special medical measures (such as termination of pregnancy) just because of the vaccination of new coronavirus vaccine, and it is recommended to do a good job of pregnancy examination and follow-up

.

For women who have a pregnancy plan, it is not necessary to delay the pregnancy plan just because of the new coronavirus vaccine

.

Although there is no clinical research data on the impact of new coronavirus vaccination on lactating infants among lactating women, based on the understanding of the safety of the vaccine, it is recommended to vaccinate lactating women (such as medical staff) with high risk of new coronavirus infection

.

Considering the importance of breast-feeding to infant nutrition and health, referring to the international practice, it is suggested that breast-feeding should be continued after breast-feeding women are vaccinated with new coronavirus vaccine

.

05 immune function impaired people immune function impaired people are infected with new coronavirus after severe, high risk of death.

.