The third dose of novel coronavirus vaccine booster injection, do you want to play?

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Due to the worldwide raging of the variant COVID-19 Delta, most of the world is still in the shadow of the epidemic

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Some countries have announced or are considering a new dose of third vaccine for some people

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However, some researchers said that although the third dose of reinforcing needle can enhance the immune response, it is not necessary

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Whether to take the third dose of reinforcing injection has become a topic discussed by governments and scientific research circles

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Why do you need a booster injection? This is because the protective effect of some vaccines may weaken over time

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In order to provide additional protection, it is necessary to vaccinate again to stimulate the body to produce and improve the antibody level

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For many vaccines against viral infection, booster shots are common, such as the influenza vaccine with booster shots once a year

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Another reason why people may need to get a novel coronavirus vaccine booster shot is the virus mutation

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A spokesman for the University of Oxford’s novel coronavirus vaccine team said that some of the variant strains had evolved to avoid some of the body’s immune responses, which means they could more easily infect people who had recovered or had been vaccinated against the novel coronavirus virus

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However, the virus cannot avoid all immune reactions in the human body

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Booster injections are helpful because they can enhance some immune responses that the mutant strain cannot avoid

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There is also a view that booster injections may be beneficial to the elderly or people with weak immune system, because their bodies may not produce a strong enough immune response after earlier vaccination, but there is still need to be evidence to prove that booster injections are safe and effective for these people

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The Pfizer Inc and the German biotech New Technologies Inc issued a joint statement in July 8th, saying that the injection of Pfizer vaccine (BNT162b2) third booster needle is expected to help the human body increase the resistance to various variants of COVID-19, including the delta strain

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According to the statement, the initial data of the third dose vaccine test showed that the human body injected third doses after second months of inoculation, and the neutralizing antibody against COVID-19 and mutant beta strain in the body increased by 5 to 10 times than that of the two inoculant two months after inoculating second doses

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The statement said that the data of papers recently published in the British journal Nature showed that the test found that after the second dose of Pfizer vaccine, the human body had a high level of neutralizing antibody to delta virus strain

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The two companies expect that the third dose will further improve the level of such antibodies, which is currently being verified through preclinical and clinical trials

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The data previously released by the Israeli Ministry of health showed that the protective effect of Pfizer vaccine decreased six months after vaccination, but it still had a significant effect in preventing severe diseases

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Based on the existing data, the two companies believe that a third dose may need to be injected within 6 to 12 months after the completion of the two doses of vaccination to continue to provide protection for the human body

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The Israeli Ministry of Health announced on July 12 that it would provide the third dose of novel coronavirus vaccine for those with low immunity in the country

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As the number of people who completed the two doses of vaccination increased, the British government also began to consider implementing the third dose of booster injection plan as soon as possible

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According to the news released by the British Ministry of health on June 30, the Joint Committee on vaccination and immunization of the independent expert group of the government suggested that the third dose of booster injection should be given to the most vulnerable people in the epidemic in September, so as to strengthen the protection of these people before this winter

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However, the British Ministry of health also said that with the continuous data analysis, the committee’s final recommendations may change

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At present, the UK is evaluating the effect of the booster injection of the novel coronavirus vaccine through clinical trials

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It is expected that the research team will announce the preliminary results of this clinical trial in September this year

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According to a preprinted paper recently published by the “social science research network” of the United States, Oxford University researchers took AstraZeneca vaccine as the research object and found that vaccination with the third dose of vaccine can greatly enhance the immune response

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But they also said that there was no indication that a third dose of booster injection was needed, and stressed that the “top priority” was to ensure that people around the world received the first dose of vaccine

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The World Health Organization also said there was not enough evidence that a third dose of vaccine was needed

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Pharmaceutical companies such as Pfizer should focus on providing vaccines to countries that do not have access to the first dose of vaccine, rather than providing booster shots to vaccinated people in rich countries

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Jay Butler, deputy director of infectious disease prevention and control at the Centers for Disease Control and prevention, believes that for those who have been fully vaccinated, the third dose of vaccine may bring a higher risk of adverse reactions

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However, at this stage, there is not enough data to determine whether this will happen

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The U.S

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Centers for Disease Control and prevention and the U.S

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Food and Drug Administration jointly issued a statement on July 8 that Americans who have completed two doses of vaccination do not need to be vaccinated with a third dose at present, but if science proves that they really need to strengthen the injection, the two departments are “ready”

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Subsequently, the European drug administration also issued a document saying that it is “too early” to judge whether and when a third dose of vaccine is needed

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Antony Fauci, director of the National Institute of allergy and infectious diseases, said on July 11 that “in view of the data and information currently available, we do not need to vaccinate the people with the third dose (novel coronavirus vaccine)”, “a number of studies are being carried out on whether and when to strengthen the injection.” Source: Xinhuanet welcome to apply for Shanxi Yuncheng Huamei technical school to give you a wonderful future

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