Look! Contraindications and related precautions of 42 novel coronavirus vaccines

What are the contraindications of novel coronavirus vaccination? What circumstances suggest vaccination? What suspension of vaccination? What are the precautions? To understand the vague understanding of the control of contraindications in the implementation of the vaccination strategy for COVID-19 vaccine, and to reduce the loss of audience and the contradiction between doctors and patients caused by improper holding of contraindications.

According to the “novel coronavirus virus vaccination technology guide (First Edition)” issued by the national health and Health Committee, and the contents of the informed consent and the vaccine instructions, the contraindications and related issues of the novel coronavirus vaccination are further combed and clarifies.

Let’s take a look.


Persons with severe allergic reactions (such as acute allergic reaction, angioneuroedema, dyspnea, etc.) caused by previous vaccination cannot be vaccinated.


People who are allergic to vaccine ingredients and excipients cannot be vaccinated.

Excipients of inactivated novel coronavirus vaccine mainly include disodium hydrogen phosphate, sodium chloride, sodium dihydrogen phosphate and aluminum hydroxide.


People who are allergic to dust mites, food (eggs, peanuts, seafood, Mango), pollen, alcohol, penicillin, cephalosporin or other drugs can be inoculated.


For fever (axillary temperature ≥ 37.3 ℃) caused by any reason (cold, wound infection, local inflammation), the vaccination shall be postponed.


During the acute attack of gout, severe cold, myocardial infarction, cerebral infarction and other diseases, the vaccination shall be postponed.


Heart disease, coronary heart disease, coronary atherosclerosis and other diseases, which are not acute attack, can be inoculated.


Chronic patients with stable health status and good drug control are not considered as taboo population for novel coronavirus vaccination, and vaccination is recommended.


Patients with acute attack of chronic diseases or uncontrolled severe chronic diseases cannot be vaccinated.


The control of hypertension drugs is stable, and the blood pressure is lower than 160 / 100mmhg, so it can be inoculated.


diabetes drug control is stable, fasting blood glucose is less than 13.9mmol/L, can be vaccinated.


Patients with hypothyroidism take the stabilizer amount of levothyroxine (youjiale).

Their thyroid function is normal and can be vaccinated.


Chronic eczema has no obvious attack and can be inoculated.


The current symptoms of chronic urticaria are not obvious and can be vaccinated.


If the symptoms of chronic rhinitis are not obvious, it can be inoculated.


Chronic hepatitis does not need to be treated with medicine.

If the liver function is normal, it can be vaccinated.


Tuberculosis is not active and can be vaccinated.


Psoriasis is non pustular and other acute types, which can be inoculated.


Chronic obstructive pulmonary disease is not in acute attack stage, and there is no obvious cough and asthma.

It can be inoculated.


Ankylosing spondylitis has no acute pain and can be inoculated.


Depression drugs are well controlled, life and work are as usual, and can be vaccinated.


all kinds of drugs used in the treatment of diabetes, including insulin injection, are not taboos for vaccination.


Before and after surgery, patients with malignant tumors are undergoing chemotherapy and radiotherapy, and vaccination is suspended.


The general principle of immune system diseases (systemic lupus erythematosus, rheumatoid arthritis, ankylosing spondylitis, Sjogren’s syndrome, etc.) is cautious vaccination.

Generally speaking, novel coronavirus inactivated vaccine and recombinant subunit vaccine can be vaccinated when the disease is stable.


Radiotherapy and chemotherapy will not be carried out for more than three years after malignant tumor operation; Nephrotic syndrome; Take immunosuppressive drugs after renal transplantation; AIDS patients and HIV infected persons are advised to inoculate inactivated vaccine and recombinant subunit vaccine.


Those suffering from uncontrolled epilepsy and other serious nervous system diseases (such as transverse myelitis, Guillain Barre syndrome, demyelinating disease, etc.) shall be suspended from vaccination.


Vaccination can be given during menstrual period, pregnancy preparation period and lactation period, and continue lactation.


Pregnancy cannot be vaccinated.


If it is found that pregnancy does not need to be terminated after vaccination, it is recommended to do a good job in pregnancy examination and follow-up.


Men do not have the problem of being unable to receive the novel coronavirus vaccine due to pregnancy preparation.


The novel coronavirus vaccine is not recommended to be vaccinated at the same time as other vaccines.

The vaccination interval between other vaccines and novel coronavirus vaccine should be greater than 14 days.


In any case, when it is necessary to vaccinate rabies vaccine, tetanus vaccine, rabies immunoglobulin and tetanus immunoglobulin due to animal injury, trauma and other reasons, the interval shall not be considered, and the above vaccines and immunoglobulins shall be vaccinated preferentially.


If rabies vaccine, tetanus vaccine, rabies immunoglobulin, tetanus immunoglobulin, etc.

are vaccinated first, the last vaccination of the above vaccines shall be completed first, and the novel coronavirus vaccine can be vaccinated after an interval of 14 days.


People injected with human immunoglobulin should be vaccinated at least one month apart to avoid affecting the immune effect.


patients with previous novel coronavirus pneumonia (patients or asymptomatic infections) could receive 1 new dose of vaccine after 6 months on the basis of full disclosure.


there is no need for COVID-19 nucleic acid and antibody detection before vaccination.


Routine detection of antibodies after vaccination is not recommended as a basis for the success of immunization.


At this stage, it is recommended to complete vaccination with the same vaccine product.


If the vaccine cannot be continuously supplied in this city or vaccinated in other places, and the vaccination cannot be completed with the same vaccine product, the vaccine products of other manufacturers of the same kind can be used to complete the vaccination (such as Zhongsheng Beijing Institute, Zhongsheng Wuhan Institute and Kexing Zhongwei replacement).


Two doses of inactivated vaccine are required.

If it is not completed according to the procedure, it is recommended to reseed as soon as possible.

There is no need to restart the immunization procedure, and 2 doses of reseeding can be completed.


If two doses of inactivated vaccine are completed in 14-21 days, there is no need to reseed.


Strengthening immunization is not recommended at this stage.

Two injections of inactivated vaccine were completed according to the procedure, and it will not be strengthened.


For other information, please consult the doctor at the vaccination site…